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Angels vs. Guardians prediction, odds, time: 2026 MLB picks for Monday, May 11 from proven model
TL;DR
The Cleveland Guardians host the Los Angeles Angels on May 11, 2026, with first pitch at 6:10 p.m. ET. Cleveland is favored at -175, with an over/under of 7.5 runs.
Key points
- Cleveland Guardians lead AL Central
- Los Angeles Angels have won three of five games
- Joey Cantillo starts for Guardians
- Alek Manoah expected to pitch for Angels
- Game starts at 6:10 p.m. ET
Cleveland GuardiansLos Angeles AngelsJose RamirezMike Trout
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Jose Ramirez and the AL Central-leading Cleveland Guardians resume a nine-game homestand when they begin a series with Mike Trout and the Los Angeles Angels on Monday. The Guardians (21-21) remain in the lead in the Central despite dropping two of three vs. the rival Twins over the weekend. The Angels (16-25) have won three of five, including a 6-1 win over the Blue Jays on Sunday. Left-hander Joey Cantillo (2-1, 3.43 ERA) gets the ball for Cleveland. Alek Manoah is expected to follow the opener in his second appearance of the season for the Angels.
First pitch from Progressive Field in Cleveland is set for 6:10 p.m. ET. Cleveland is a -175 favorite on the money line (risk $175 to win $100) in the latest Angels vs. Guardians odds, while the over/under is 7.5. Before making any Guardians vs. Angels picks, be sure to see the Angels vs. Guardians predictions and betting advice from SportsLine's proven computer model.
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The SportsLine Projection Model simulates every MLB game 10,000 times, and is coming off a 5-0 week on top-rated MLB picks. It also excelled at making home run prop picks in 2025, returning nearly 30 units of profit. Anybody following itsĀ MLB bettingĀ picks atĀ sportsbooksĀ and onĀ betting sitesĀ could have seen strong returns.
Now, the model has set its sights on Angels vs. Guardians and just locked in its picks and MLB predictions.Ā . Here are severalĀ Ā and betting lines for Guardians vs. Angels:
Q&A
What time does the Angels vs. Guardians game start on May 11, 2026?
The game starts at 6:10 p.m. ET.
What are the betting odds for the Angels vs. Guardians game?
Cleveland is a -175 favorite on the money line, with an over/under of 7.5 runs.
Who is starting for the Guardians against the Angels on May 11, 2026?
Left-hander Joey Cantillo is starting for the Guardians.
What is the current record of the Angels and Guardians as of May 11, 2026?
The Guardians have a record of 21-21, while the Angels are 16-25.