Day 2 mock draft: Who do experts think the 49ers will take?

The 49ers should start planning for life after Trent Williams. Barber (6-7, 318 pounds) is a tall tackle who was a three-year starter on the left side at Florida. He is a great run blocker but will need to improve against speed rushers at the NFL level.

Sports Illustrated's Daniel Flick

Round 2, Pick No. 33: Edge Zion Young, Missouri

The 49ers traded out of the first round and likely will field plenty of offers for this pick on Friday night, but Young fits the build of a traditional San Francisco pass rusher. The 49ers finished last in the league in sacks in 2025, and Young has the juice to elevate the unit this fall.

Round 2, Pick No. 58: OG Emmanuel Pregnon, Oregon

The 49ers may consider a tackle, but they need help on the interior, too. Pregnon, who stands 6' 4" and 314 pounds, has four years of starting experience at guard and brings a tough, physical presence.

Round 3, Pick No. 90: WR Brenen Thompson, Mississippi State

ESPN's Matt Miller

Round 2, Pick No. 33: S Emmanuel McNeil-Warren, Toledo

The 49ers moved out of Round 1, but the chance to take the player I originally predicted for them is still here as McNeil-Warren slips to Round 2. After watching rival Seahawks safety Nick Emmanwori neutralize offenses, former safety and 49ers general manager John Lynch can draft his own version.

Round 2, Pick No. 58: WR Antonio Williams, Clemson

San Francisco added Mike Evans in free agency, and they like Ricky Pearsall as a deep threat, but an intermediate option from the slot is needed. Williams is a precise route runner with consistent hands and yards-after-catch ability.

Round 3, Pick No. 90: OT Markel Bell, Miami

CBS Sports's Josh Edwards

Round 2, Pick No. 33: Edge R Mason Thomas, Oklahoma

Thomas is a personal favorite in this draft class and has been on my radar since his high school days, when he was a late riser. He brings so much energy to the field and is relentless in pursuit of the quarterback. There are so many in this class who can set the edge, but not push the pocket or push the pocket, but not set the edge. Thomas is one I'd want in my corner to potentially grow into that well-rounded starter.

Round 2, Pick No. 58: WR Chris Bell, Louisville

Among Day 2 options at the wide receiver position, Bell has arguably the most potential. He has great size and is dynamic with the ball in space. There is absolutely some boom or bust potential with him coming off an injury, but he could develop into something more than the complementary receiver often found on Day 2.

The Athletic's Nick Baumgardner

Round 2, Pick No. 33: S Emmanuel McNeil-Warren, Toledo

McNeil-Warren was a top-30 player on my final board and would check off a need for the 49ers, who moved out of the first round after missing out on “a couple of players” they had targeted, according to GM John Lynch. The best tackles in this draft are now gone, so it might make sense for San Francisco to check off another need here first.

Round 2, Pick No. 58: OT Caleb Tiernan, Northwestern

If there’s a tackle worth taking in Round 2 this year, it’s Tiernan. The hulking 6-7, 323-pounder has an outstanding work ethic and an even better anchor.

Round 3, Pick No. 90: Edge Dani Dennis-Sutton, Penn State

Pro Football Focus' Bradley Locker

Round 2, Pick No. 33: WR Denzel Boston, Washington

The 49ers could opt for a tackle or edge defender here, but they displayed heavy interest in receivers with their documented top-30 visits — which makes sense given their need for more depth at the position. Boston’s blend of separation skill, contested catch ability (career 76.9% rate) and run-blocking prowess (77.1 grade in 2025) feel like too much to pass up for Kyle Shanahan considering the team lacks reliably healthy options out wide.

Round 2, Pick No. 58: Edge Gabe Jacas, Illinois

After acquiring Denzel Boston at the top of the second round, San Francisco will presumably add a defensive playmaker at Pick 58. Jacas’ 88.0 PFF pass-rush grade and 14.9% pass-rush win rate are needed on a 49ers front that ranked 23rd in pass-rush grade at the position — especially after losing Bryce Huff to retirement.

This article originally appeared on Niners Wire: Day 2 mock draft: Who do experts think the 49ers will take?