Dodgers vs Giants Prediction: Odds, recent stats, trends, and best bets for April 21

TL;DR

The Los Angeles Dodgers (16-6) face the San Francisco Giants (9-13) at Oracle Park on April 21. The Dodgers lead MLB in several offensive categories, while the Giants struggle with home runs.

Key points

Dodgers have a record of 16-6.
Giants have a record of 9-13.
Dodgers lead MLB in batting average, home runs, and RBI.
Giants hit the fewest home runs in the league.
Game is at Oracle Park.

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Oracle Park

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Dodgers vs Giants Prediction: Odds, recent stats, trends, and best bets for April 21

The San Francisco Giants (9-13) host the Los Angeles Dodgers (16-6) at Oracle Park for a three-game series.

Los Angeles split the series with Colorado, but is coming off a 12-3 win. The Dodgers outscored the Rockies, 28-17 despite going 2-2. The Dodgers lead the MLB in batting average (.293), home runs (42), RBI (128), and hits (222).

San Francisco had its three-game winning streak snapped in a 3-0 loss to Washington on Sunday. The Giants will need more offense against the Dodgers. San Francisco is hitting the fewest amount of home runs (13) despite having the 10th-best batting average (.251).

Let's dive into the matchup and find a sweat or two.

We’ve got all the info and analysis you need to know ahead of the game, including the latest info on the how to catch first pitch, odds, recent team performance, player stats, and of course, our predictions, picks & best bets for the game from our modeling tools and staff of experts.

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Game details & how to watch Dodgers at Giants

Date: Tuesday, April 21, 2026
Time: 9:45 PM EST
Site: Oracle Park
City: San Francisco, CA
Network/Streaming: MLB TV

Q&A

What are the current odds for the Dodgers vs Giants game on April 21?

The current odds for the Dodgers vs Giants game have not been specified in the excerpt.

What recent performance trends should I consider for the Dodgers and Giants?

The Dodgers recently split a series with the Rockies but won 12-3, while the Giants had a three-game winning streak snapped by a loss to Washington.

How do the Dodgers and Giants compare in batting statistics?

The Dodgers lead MLB in batting average (.293), home runs (42), and RBI (128), while the Giants have the fewest home runs (13) despite a decent batting average (.251).

Where is the Dodgers vs Giants game being played?

The game is being played at Oracle Park in San Francisco.