Free MLB home run picks, odds, predictions for May 16: Kyle Schwarber among top HR prop bets on Saturday

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Everybody's working for the weekend, and with 15 MLB games on tap on Saturday, May 16, the top sluggers in the game are working to hit the ball out of the yard. There's no shortage of MLB betting opportunities for sports bettors, including player props like home run picks. After taking a look at all 15 games on the schedule and the pitchers set to take the mound, we've picked two players for our best home run bets today, and both are National League sluggers off to incredible starts to 2026. These two stand out as our best bets to hit a home run today.

For even more MLB expert picks and predictions, make sure you see what the SportsLine Projection Model has to say.

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Best home run picks for Saturday, May 16

• Kyle Schwarber, Philadelphia Phillies (+225)
• Ildemaro Vargas, Arizona Diamondbacks (+725)

Kyle Schwarber, Phillies (+225, FanDuel)

It's a year that ends with a number, which means Schwarber is doing what he does best -- hitting dingers. And Saturday is a day that ends with a 'Y,' so Schwarber is once again a threat to go deep. The 2025 NL MVP runner-up is back to his slugging ways after swatting 56 last year, as he enters the weekend with 20 homers on the year, the most in baseball, and he homered three times over the last two days. Schwarber has hit 14 of those home runs off right-handed pitching, and he's got a favorable matchup on Saturday with the set to start , Chandler, a young right-hander, has given up four home runs over his last four starts and six over his last six. Four of those homers have come to left-handed hitters, which bodes very well for Schwarber on Saturday.