The Baltimore Orioles (9-9) face the Cleveland Guardians (10-9) in a four-game series, both teams looking to end two-game losing streaks. The Orioles are struggling offensively, while the Guardians have emerging talent in their lineup.
Key points
Orioles and Guardians both on two-game losing streaks
Orioles vs. Guardians prediction: Odds, recent stats, trends, and best bets for April 16
The Baltimore Orioles (9-9) kick off a four-game series against the Cleveland Guardians (10-9) at Progressive Field tonight. Each team takes the field looking to snap a two-game losing streak.
Inconsistency has been a staple unfortunately for both clubs. The Orioles are 4-6 in their last 10, while the Guardians sit at 5-5 in their last 10 games.
Offensively, the Orioles are led by Gunnar Henderson who boasts a team-leading six home runs but who is hitting just .221 for the season. Pete Alonso was the big offseason free agent signing made by Baltimore this past offseason. The Polar Bear has yet to get on track hitting just .197 with two home runs. The Guardians are no longer overly reliant on Jose Ramirez. Angel Martinez is hitting .302 in his second full season in the majors. Rookie Chase Delauter has five home runs and 12 RBIs.
Tonightâs starters are Shane Baz for Baltimore and Parker Messick for the Guardians. Baz is making his fourth start of 2026. The 26-year-old will be looking to offer more than he has in his previous three starts as he has not pitched a full six innings yet this season. The southpaw Messick has gotten off to a hot start for Cleveland. The 25-year-old lefty has been dominant, limiting opponents to just one earned run and 11 hits over 17.2 innings.
Lets dive into tonightâs matchup and find a sweat or two.
Weâve got all the info and analysis you need to know ahead of the game, including the latest info on the how to catch first pitch, odds, recent team performance, player stats, and of course, our predictions, picks & best bets for the game from our modeling tools and staff of experts.
Q&A
What are the latest odds for the Orioles vs. Guardians game on April 16?
The latest odds for the Orioles vs. Guardians game are not specified in the excerpt, but both teams are looking to improve their standings.
Who are the key players to watch in the Orioles vs. Guardians matchup?
Key players include Gunnar Henderson for the Orioles, who has six home runs, and Jose Ramirez for the Guardians, alongside rookie Chase Delauter.
What are the recent performance trends for the Orioles and Guardians?
The Orioles are 4-6 in their last 10 games, while the Guardians have a record of 5-5 in the same span.
How have the Orioles and Guardians performed offensively this season?
The Orioles are struggling with a team batting average of .221, while the Guardians have players like Angel Martinez hitting .302.
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The Latest Odds: Orioles vs. Guardians
The latest odds as of Thursday courtesy ofDraftKings:
Pete Alonso has 6 extra base hits this season in 66 ABs
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Top Betting Trends & Insights: Orioles vs. Guardians
The Orioles are 7-11 on the Run Line this season
The Guardians are 11-8 on the Run Line this season
The OVER has cashed 10 times in the Oriolesâ 18 games this season (10-8)
The OVER has cashed 9 times in the Guardiansâ 19 games this season (9-10)
If youâre looking for more key trends and stats around the spread, moneyline and total for every single game on the schedule today, check out our MLB Top Trends tool on NBC Sports!
Expert picks & predictions: Orioles vs. Guardians
Rotoworld Bet Best Bet
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Our model calculates projections around each moneyline, spread and over/under bet for every game on the MLB calendar based on data points like past performance, player matchups, ballpark information and weather forecasts.
Once the model is finished running, we put its projection next to the latest betting lines for the game to arrive at a relative confidence level for each wager.
Here are the best bets our model is projecting for Thursdayâs game between the Orioles and the Guardians:
Moneyline: Rotoworld Bet is recommending a play on the Guardians on the Moneyline.
Spread: Rotoworld Bet is leaning towards a play on the Guardians on the Run Line.
Total: Rotoworld Bet is staying away from a play on the Game Total of 8.0.
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