
Miller's final NFL mock draft -- with Fowler's latest intel: Projecting 32 first-round picks
Check out the final predictions for the 2026 NFL Draft, starting at 8 p.m. ET!
The Chicago Cubs, currently on a seven-game winning streak, face the struggling Philadelphia Phillies, who have lost seven consecutive games. The Cubs aim to clinch the series with a win today.
Phillies vs Cubs Prediction: Odds, recent stats, trends and best bets for April 22
The Chicago Cubs (14-9) reach seven games on their winning streak following a 7-4 victory over Philadelphia (8-15) and extends their losing streak to seven games. With a win today, Chicago would clinch the series versus Philadelphia.
The Cubs have scored at least seven runs in six out of the past nine games. Chicago's offense has heated up with the third-best batting average (.282) and fifth-most home runs (8) in the last week.
Philadelphia has the second-worst batting average (.177) in the MLB over the past week along with the fewest hits (29). The Phillies losing streak has hit seven games and they are 2-9 over the previous 11 contests.
Lets dive into the matchup and find a sweat or two.
Weâve got all the information and analysis you need to know ahead of the game, including the latest details on the how to catch first pitch, odds, recent team performance, player stats and of course, our predictions, picks and best bets for the game from our modeling tools and staff of experts.
Follow Rotoworld Player News for the latest fantasy and betting player news and analysis all season long.
Game details and how to watch Phillies at Cubs
Never miss a second of the action and stay up-to-date with all the latest team statistics and player news. Check out our day-by-day MLB schedule page, along with detailed matchup pages that update live in-game with every out.
The current odds for the game are not specified in the provided text.
The Cubs have won their last seven games, including a 7-4 victory over the Phillies in their most recent matchup.
The Phillies have the second-worst batting average in the MLB at .177 over the past week, with only 29 hits.
The Cubs have scored at least seven runs in six of their last nine games, boasting the third-best batting average of .282 in that span.

Check out the final predictions for the 2026 NFL Draft, starting at 8 p.m. ET!

Nuggets on McDaniels' 'bad defenders' jab: 'Let them talk'

Caitlin Clark plans to reduce ball handling to stay fresh in 2026.
See every story in Sports â including breaking news and analysis.
Odds for Phillies vs. Cubs
The latest odds as of Wednesday:
Probable starting pitchers for Phillies at Cubs
2026 stats: 6.2 IP, 0-0, 5.40 ERA, 1.20 WHIP, 9 Ks, 1 BB
2026 Stats: 9.1 IP, 1-1, 6.75 ERA, 1.18 WHIP, 17 Ks, 3 BB
Whoâs Hot? Whoâs Not?
Rotoworld still has you covered with all the latest MLB player news for all 30 teams. Check out the feed page right here on NBC Sports for headlines, injuries and transactions where you can filter by league, team, positions and news type!
Top betting trends & insights to know ahead of Phillies at Cubs
If youâre looking for more key trends and stats around the spread, moneyline and total for every single game on the schedule today, check out our MLB Top Trends tool on NBC Sports!
Expert picks and predictions for tonightâs game between Phillies and Cubs
Rotoworld Bet Best Bet
Please bet responsibly. If you or someone you know has a gambling problem, call the National Gambling Helpline at 1-800-522-4700.
Our model calculates projections around each moneyline, spread and over/under bet for every game on the MLB calendar based on data points like past performance, player matchups, ballpark information and weather forecasts.
Once the model is finished running, we put its projection next to the latest betting lines for the game to arrive at a relative confidence level for each wager.
Here are the best bets our model is projecting for Wednesday's game between the Phillies and the Cubs.
Follow our experts on socials to keep up with all the latest content from the staff: