The Red Sox face the Tigers on May 6, with Boston leading the series 2-0. Framber Valdez may face suspension after a controversial incident, while Sonny Gray is expected to return for the Red Sox.
Key points
Red Sox lead series against Tigers 2-0
Framber Valdez may face suspension for beaning Trevor Story
Sonny Gray expected to start for Red Sox
Ceddanne Rafaela homered and drove in four runs
Tigers have better overall batting average this season
Red SoxTigersFramber ValdezTrevor Story
Red Sox vs. Tigers prediction: Odds, recent stats, trends, and best bets for May 6
With Framber Valdez facing a potential suspension following last nightâs beaning of Trevor Story the shorthanded Tigers (18-19) take on the Red Sox (15-21) tonight at Comerica Park. Boston has taken the first two games in this series including last nightâs 10-3 pasting of Detroit. Ceddanne Rafaela was the catalyst for the Sox on offense homering and driving in four runs. Brayan Bello allowed one run over seven innings to secure his second win of the season. The story, though, was the poor performance by Valdez (10 runs, 7 earned over 3 innings) and his four-seam fastball (the first he had thrown all season) he put in the upper back of Story. A franchise that lost ace Tarik Skubal earlier in the week may well be without Valdez for a handful of games. Stay tuned.
Boston has outscored Detroit 15â7 in the first two games of this series. The Red Sox lineup seems to be awakening with Willson Contreras (5-10) and Wilyer Abreu (4-8) leading the way in this series. Detroitâs bats have been better overall this season than Bostonâs scoring 20 more runs in their first 37 games. Rookie has been consistent for the Tigers hitting .327 in April as a follow-up to a .333 average in March.
Q&A
What are the odds for the Red Sox vs. Tigers game on May 6?
The specific odds for the game have not been detailed, but the Red Sox are currently favored after winning the first two games of the series.
Who is starting for the Red Sox against the Tigers on May 6?
Sonny Gray is expected to start for the Red Sox against Jack Flaherty of the Tigers.
What happened with Framber Valdez in the Red Sox vs. Tigers game?
Framber Valdez faced a potential suspension after hitting Trevor Story with a pitch during the game.
How have the Red Sox performed against the Tigers in their recent games?
The Red Sox have outscored the Tigers 15-7 in the first two games of the series, indicating strong offensive performance.
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Kevin McGonigle
The Red Sox expect to activate Sonny Gray before the game and send him to the bump. He will be opposed by Jack Flaherty.
Lets dive into tonightâs matchup and find a sweat or two.
Weâve got all the info and analysis you need to know ahead of the game, including the latest info on the how to catch first pitch, odds, recent team performance, player stats, and of course, our predictions, picks & best bets for the game from our modeling tools and staff of experts.
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Game Details and How to Watch: Red Sox vs. Tigers
Date: Wednesday, May 6, 2026
Time: 6:40PM EST
Site: Comerica Park
City: Detroit, MI
Network/Streaming: MLB.TV, NESN, Tigers.TV
Never miss a second of the action and stay up-to-date with all the latest team stats and player news. Check out our day-by-day MLB schedule page, along with detailed matchup pages that update live in-game with every out.
The Latest Odds: Red Sox vs. Tigers
The latest odds as of Wednesday courtesy ofDraftKings:
Kevin McGonigle is slumping for the first time in the major leagues going just 3-17 in May
Riley Greene has hit safely in 4 of his last 5 games (6-18)
Rotoworld still has you covered with all the latest MLB player news for all 30 teams. Check out the feed page right here on NBC Sports for headlines, injuries and transactions where you can filter by league, team, positions and news type!
Top Betting Trends & Insights: Red Sox vs. Tigers
The Tigers are 12-5 at home this season
The Red Sox are 9-11 on the road this season
The Tigers are 19-18 on the Run Line this season
The Red Sox are 12-24 on the Run Line this season
The OVER has cashed 18 times in Boston games this season (18-17-1)
The OVER has cashed 18 times in Tigersâ games this season (18-17-2)
If youâre looking for more key trends and stats around the spread, moneyline and total for every single game on the schedule today, check out our MLB Top Trends tool on NBC Sports!
Expert picks & predictions: Red Sox vs. Tigers
Rotoworld Bet Best Bet
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Our model calculates projections around each moneyline, spread and over/under bet for every game on the MLB calendar based on data points like past performance, player matchups, ballpark information and weather forecasts.
Once the model is finished running, we put its projection next to the latest betting lines for the game to arrive at a relative confidence level for each wager.
Here are the best bets our model is projecting for tonightâs game between the Red Sox and the Tigers:
Moneyline: Rotoworld Bet is leaning towards a play on the Red Sox on the Moneyline.
Spread: Rotoworld Bet is staying away from a play on the Run Line
Total: Rotoworld Bet is recommending a play on the Game Total OVER 8.5 runs
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