San Diego drops rubber match for first road series loss of the season

Hancock is off to a *fantastic* start to the season with the Mariners. He’s headlined a rotation full of elite pitchers who have made way for the breakout righty. Entering play on Friday, Hancock boasts a 3.21 ERA and 1.01 WHIP in 47 2/3 innings. The Friars faced Hancock in their last series against Seattle, and he managed to hold them to two runs over six innings. San Diego ended up winning that game with a five-run ninth-inning rally, but Hancock wasn’t the cause of that. The offense will need to come alive if they hope to scratch some runs against the right-hander. Similarly, Vásquez has been a breakout pitcher in the San Diego rotation. The righty sports a 3.05 ERA in 44 1/3 innings. The WHIP is a little high at 1.17, but he’s managed to strand the baserunners he picks up most of the time. Vásquez also faced Seattle in that last series, but it went much worse for him than it did for Hancock. It was the right-hander’s first poor start of 2026, allowing four runs in the same number of innings. The Padres still ended up winning, but they’ll need a better performance from Vásquez this time around if they hope to save their beleaguered bullpen.

Batter up!

Manager Craig Stammen has been making his lineups as offense focused as possible lately, having Fernando Tatis Jr. play second base quite often so Nick Castellanos and Miguel Andujar’s bats can remain in the lineup. That hasn’t worked, so it’s possible they try something different in this series.

1. Xander Bogaerts, SS
2. Jackson Merrill, CF
3. Miguel Andujar, DH
4. Gavin Sheets, 1B
5. Manny Machado, 3B
6. Fernando Tatis Jr., RF
7. Ramón Laureano, LF
8. Sung-Mun Song, 2B
9. Rodolfo Durán, C I know, I know. Putting Machado in the fifth spot feels blasphemous. But he’s batting .190 on the year. He cannot keep hitting in the three and four spots as if that still makes sense. The same goes for Tatis, who has had an incredibly streaky start to the year mostly because of poor hitting mechanics. Bogaerts and Merrill, on the other hand, have a career .429 and .400 batting average against Hancock. Sheets owns a 1.232 OPS. If they can show up tonight against Seattle, the San Diego starter might be able to pitch with a lead for the first time in a while.

Relief corps

With Canning unable to make it through two innings, Ron Marinaccio, Yuki Matsui and Matt Waldron covered the rest of the Padres’ loss on Thursday. The three pitched well, only giving up one run in that time frame. Despite Stammen stating that Waldron will continue to pitch out of the ‘pen, Kevin Acee of the San Diego Union-Tribune reported that Waldron will be designated for assignment. Acee also reports that the Padres will call up reliever Alek Jacob to pitch out of the ‘pen until starter Lucas Giolito is added to the roster this weekend. For tonight’s series opener, the high-leverage relievers are out in full force. Jason Adam, Jeremiah Estrada, Mason Miller, Adrian Morejon and Wandy Peralta are all available out of the ‘pen tonight. But, hopefully, Vásquez can pitch deep enough that Stammen won’t need to call on too many of those arms.