What are the best and worst Titans' draft picks of the past 25 years?

The NFL draft is just three days away, and the smokescreens are rising across the league in what could be one of the most unpredictable drafts in recent memory.

The Tennessee Titans will be on the clock early, and at this point, there are way too many variables to truly decipher what they will do with this all-important haul. While they have some holes to fill, they are in a better place than when they kicked off the offseason.

With the next group of rookies preparing to come to Nashville, Bryan DeArdo took a look back at the past 25 drafts and found the best and worst of the Titans' draft classes since the year 2000.

**Tennessee Titans**Best pick: RB Derrick Henry (No. 45 overall, 2016)

After a quiet first two seasons in Nashville, Henry quickly became one of the greatest running backs in NFL history. He won back-to-back rushing titles with the Titans, which included a season that saw him become the eighth player to run beyond 2,000 yards in a season. With the Ravens, Henry had the greatest season in NFL history by a running back over the age of 30 in 2024 when he ran for 1,921 yards.

In 2026, Henry could conceivably pass four running backs to move into sixth place on the NFL's all-time career rushing list.

Worst pick: OT Isaiah Wilson (No. 29 overall, 2020)

Barring injury, not many first-round picks end up playing in just one regular-season NFL game. Discipline issues, however, led to Wilson's career amounting to just one game. He was traded to the Dolphins for a seventh-round pick in 2021 but was released just three days later after showing up late for his physical and missing two workouts.

Landing King Henry in the second round was a homerun. A rare combination of size and speed, he was not only the face of the franchise, but he has also proven to be one of the most dominant backs of his generation.