The Seattle Mariners are set to face the San Diego Padres in the first game of a three-game series, with the Mariners favored to win due to their pitching advantage. The predicted moneyline for the Mariners is -114.
Two teams riding long winning streaks will look to stay hot this week as the San Diego Padres host the Seattle Mariners in the first of a three-game series tonight.
Seattle has the pitching edge in tonight’s game, and that’s enough for me to pick it to win in my Mariners vs. Padres predictions below.
Read on for my full analysis of this matchup and to get my free MLB picks for Tuesday, April 14.
Who will win Mariners vs Padres today: Mariners moneyline (-114)
Both teams come into tonight’s game following four-game sweeps over the weekend. The San Diego Padres are the hotter of the two, having now won eight of their last nine overall. But there’s no denying that the Seattle Mariners have the pitching edge tonight.
Bryan Woo has a 2.84 ERA since the start of the 2024 season, which a minuscule WHIP of 0.908 in that span. He’s struck out 17 batters while allowing just three earned runs on 10 hits over his first 18 innings of work this season.
As good as Michael King (1-1, 3.24 ERA) has been for the Padres, I like the Mariners to win behind Woo.
Covers
Covers
COVERS INTEL:
Bryan Woo has been historically dominant early in the season, holding opponents to a .523 OPS in March and April throughout his career.
Mariners vs Padres Over/Under pick: Over 7.0
The Mariners and Padres each saw their offenses wake up over the weekend. Seattle averaged 7.25 runs per game in their four-game sweep of the Houston Astros, while the Padres put up an average of 7.00 runs in their sweep of the Colorado Rockies.
None of that changes the fact that there’s a strong pitching matchup on tap tonight, but this total won’t be easy to get Under. In particular, San Diego comes in having played to a total of 7+ runs in six straight games. With both lineups coming into tonight’s game hitting well, I’m taking the Over.
Scimia's 2026 Transparency Record
ML/RL bets: 3-3, -0.03 units
Over/Under bets: 1-3, -1.96 units
Mariners vs Padres odds
Moneyline: Seattle -120 | San Diego +100
Run line: Seattle -1.5 (+145) | San Diego +1.5 (-175)
Over/Under: Over 7 | Under 7
Mariners vs Padres trend
The Mariners are 6-1 straight up in their last seven meetings with the Padres. Find more MLB betting trends for Mariners vs. Padres.
How to watch Mariners vs Padres and game info
Location
Petco Park, San Diego, CA
Date
Tuesday, April 14, 2026
First pitch
9:40 p.m. ET
TV
Mariners.TV, Padres.TV
Mariners starting pitcher
Bryan Woo (0-1, 1.50 ERA)
Padres starting pitcher
Michael King (1-1, 3.24 ERA)
Mariners vs Padres latest injuries
Mariners vs Padres weather
Odds are correct at the time of publishing and are subject to change.
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What is the predicted moneyline for the Mariners in the game against the Padres?
The predicted moneyline for the Mariners is -114.
Which team has the pitching advantage in the Mariners vs Padres game?
The Seattle Mariners have the pitching edge in the matchup against the San Diego Padres.
What are the current winning streaks of the Mariners and Padres?
Both the Seattle Mariners and San Diego Padres are riding long winning streaks heading into their game.
When is the Mariners vs Padres game taking place?
The Mariners vs Padres game is scheduled for tonight as part of a three-game series.
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