NYGiants-Cowboys Week 1 odds: New York a slight underdog in season opener

TL;DR

The New York Giants are slight underdogs against the Dallas Cowboys in their Week 1 matchup on September 13, with the Cowboys favored by 2.5 points. Betting odds show the Cowboys at -154 on the moneyline and an over/under of 48.5 points.

Key points

Giants are underdogs against Cowboys in Week 1
Cowboys favored by 2.5 points with a moneyline of -154
Giants won their last meeting 34-17 on January 4

New York GiantsDallas CowboysMiami DolphinsGreen Bay Packers

Can Big Blue make it two in a row vs. Dallas? | Getty Images The 2026 NFL schedule won’t be released in full until 8 p.m. on Thursday May 14, but the league teased out a few of the Week 1 matchups in advance of that. Big Blue has been awarded a plum Week 1 game, in prime time: The first Sunday night game of the season, at MetLife Stadium against the Cowboys on September 13. In an odd twist of scheduling, this will be consecutive games between these two teams. They met on January 4, in a largely meaningless Week 18 game that the Giants won, 34-17. In a development that should surprise nobody, betting lines are out for the Week 1 game. Here are the **FanDuel odds**: **LINE**: Cowboys (-2.5). A bet on the favored Cowboys is (-120), while a bet on the underdog Giants is (-102). **MONEYLINE:** Cowboys (-154), Giants (+130). **OVER/UNDER:** 48.5. Over is (-115) and Under is (-105).

Recent history in the series is extremely lopsided. Before the Giants’ Week 18 win in January, Dallas won nine straight contests in the series, and 16 of the prior 17. However, the Cowboys needed overtime to vanquish the Giants 40-37 in a wild shootout in Week 2 of last season. So maybe John Harbaugh’s team is entering a new, more competitive era in the series, and a point spread that’s less than a field goal is noteworthy given the history. Shootouts were the norm for Dallas last season. Offense wasn’t a problem, and figures to be a major strength again this year. But they traded Edge Micah Parsons to the prior to the start of the season, and their defense fell apart and couldn’t stop anyone all year. Dallas allowed the most points per game (30.1), third most yards per game (377), and was at or near the bottom of the league in multiple defensive categories. Shoring up that defense has been a major priority this off-season. We know all about the Giants’ offseason moves, including their impressive haul in the 2026 draft. Dallas came into the draft with the second most first round capital, trailing only the Giants. After a trade-up with from pick 12 to pick 11, they snagged Ohio State Safety , who the Giants passed on twice. They followed that up with UCF edge Malachi Lawrence at Pick 23. Dallas added additional depth in later rounds. Big D was also active in trading and free agency, adding Safety from , Edge from , and CB from the Rams, among others. If the Dallas defense can be somewhat serviceable in 2026, they could make some noise in the NFC. It’s way too early to handicap this matchup, but for gamblers who want to get in early, the window is officially open.

Q&A

What are the betting odds for the Giants vs. Cowboys Week 1 game?

The Cowboys are favored by 2.5 points, with a moneyline of -154, while the Giants are at +130.

When do the Giants and Cowboys play in Week 1 of the NFL season?

The Giants and Cowboys will face off on September 13 in a prime time game at MetLife Stadium.

How did the Giants perform against the Cowboys in their last meeting?

The Giants won their last meeting against the Cowboys 34-17 in a Week 18 game on January 4.