White Sox 7, Diamondbacks 11: Slogging to even the series

Q: What was the final score of the Diamondbacks vs. White Sox game on April 22, 2026?

The final score was Arizona Diamondbacks 11, Chicago White Sox 7.

Q: Who were the standout players in the Diamondbacks' victory over the White Sox?

Ildemaro Vargas hit two home runs and Nolan Arenado had four hits with three RBIs.

Q: How did Eduardo Rodriguez perform in the game against the White Sox?

Eduardo Rodriguez struggled, allowing three walks and two home runs in five innings pitched.

Q: What issues did the Diamondbacks face in their recent games before facing the White Sox?

The Diamondbacks had pitching struggles, allowing 21 runs in their last two games prior to facing the White Sox.

PHOENIX, ARIZONA - APRIL 22: Ildemaro Vargas #6 of the Arizona Diamondbacks high-fives teammate Jose Fernandez #11 after hitting a three-run home run against the Chicago White Sox during the second inning at Chase Field on April 22, 2026 in Phoenix, Arizona. (Photo by Chris Coduto/Getty Images) | Getty Images This season, outside of a couple hiccups, has gotten off to an excellent start for the D-Backs. After a three-game sweep at the hands of the Dodgers to open season, the team has reeled off a 13-7 record and lost consecutive games just once to the major league leading Atlanta Braves. But these last two games have been pretty ugly – particularly on the pitching side as they allowed 21 runs and the starters pitched less than five innings total while allowing 16 runs. Even for an offense that has shown an ability to score runs in bunches with a joyful dynamism, that kind of run differential is difficult to overcome. It’s also forced the team’s bullpen to cover an absurd number of innings as a result. So the D-Backs were hoping to reverse both of those trends against a (nominally) weaker opponent in the White Sox, but instead the pitching continued to struggle to contain a surprisingly feisty Chicago offense and instead had to be bailed out by an excellent offensive output. has been a particular bright spot in a pitching staff that has been surprisingly resilient so far. Of course, the bar to clear for the veteran is essentially underground given his combined 5.02 ERA and 1.534 WHIP since signing as a free agent before the 2024 season. But ever since his excellent World Baseball Classic run with Team Venezuela, Rodriguez has been on another level, working to a 1.96 ERA and 1.217 WHIP through his first four starts. There were definitely some worrying signs underneath those surface numbers – including a 4.22 FIP and 4.19 expected ERA – but I was willing to overlook them as long as he limited the baserunners and home runs. Unfortunately, neither of those results were meant to be on Wednesday evening as he walked three batters and gave up two home runs, limiting his outing to just five innings and looking much more like the pitcher who struggled through the last two seasons than the one who dominated in the WBC. In fairness, it was not a banner day for any of the pitchers on the field today. The two offenses combined to score 18 runs on 28 hits, secured 11 walks, and struck out just 13 times for the game. In the entire game, there was exactly one half inning (the visiting half of the second) that didn’t feature at least one baserunner. So it shouldn’t come as a surprise that tonight’s matchup was the team’s second game of the season to stretch over three hours in duration and it felt like it. Every time one of the fanbases might have internally asked for a clean inning, they were quickly thwarted with any of the extra base hits that seemed to be falling for everyone in both lineups. There were just three starters on each team respectively that failed to secure at least one hit in the game. Thankfully for Rodriguez and the pitching staff, the bats did not come to play around today. After Rodriguez’s rough first inning, the D-Backs quickly built a rally off a leadoff walk to Jose Fernandez, a single, and Ildemaro Vargas’ second three-run homer in as many nights. It was the first of three straight innings when the home team would score, eventually building a lead out to 8-4 going into the sixth inning. Those RBIs included another Vargas home run for two runs and a run-scoring single for Nolan Arenado – part of an incredible four-hit day with three RBIs. Even after Rodriguez left the game, the White Sox consistently showed an impressive level of working counts and find ways to take good pitches either into the stands or for soft contact that extended the innings. There was little relaxation to be had as both and failed to keep the South Siders off the board and keep the game from becoming a laugher. has been the (nearly) undisputed ace of the staff so far this year and should have an excellent opportunity to pick up his fifth victory on the young season.