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Ryan Weathers lost nine pounds due to illness but pitched a no-hitter into the seventh inning. His effort was overshadowed by a bullpen collapse, leading to a 3-2 loss against the Orioles.
BALTIMORE — Ryan Weathers got violently ill, had to quarantine from his newborn, lost nine pounds, returned to the New York Yankees rotation with his rotation spot in jeopardy and promptly took a no-hitter into the seventh inning.
Yet all the toil of a turbulent two weeks went for naught.
Weathers, the Yankees left-hander turned over a one-hit shutout with one out in the seventh to his bullpen on Monday, May 11, only to see lefty Brent Headrick give up a towering three-run home run to Baltimore Orioles DH Coby Mayo.
Gone was the two-run advantage Weathers handed him. Moments later, the Yankees were stewing in their fourth consecutive loss, a 3-2 setback to the offensively impotent Orioles, a team they steamrolled in four games in the Bronx just a week ago.
It was not the outcome the Yankees expected. Nor was it anything Weathers deserved, not at this odd point in his career.
The Athletics Lawrence Butler is tagged out by Chicago White Sox third baseman Miguel Vargas as he tires to extend his double into a triple during the eighth inning at Sutter Health Park on April 18, 2026.
Ryan Weathers got violently ill, lost nine pounds, and had to quarantine from his newborn before returning to the Yankees' rotation.
Weathers pitched a no-hitter into the seventh inning, allowing only one hit before handing over the game to the bullpen.
The Yankees lost the game 3-2 after the bullpen gave up a three-run home run in the seventh inning.
Coby Mayo hit the three-run home run that led to the Yankees' loss against the Orioles.

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Cleveland Guardians mascot Slider interacts with fans during game against the Baltimore Orioles at Progressive Field on April 17, 2026.
Washington Nationals right fielder Daylen Lile attempts to catch a ball hit for a single by the Pittsburgh Pirates' Jake Mangum during the first inning at PNC Park on April 16, 2026. The Nationals won the game, 8-7.
Milwaukee Brewers catcher Gary Sanchez wears a special chest protector to commemorate Jackie Robinson Day during the game against the Toronto Blue Jays at American Family Field on April 15, 2026.
April 13: The Pittsburgh Pirates' Spencer Horwitz celebrates a home run in the dugout while wearing a welder's hood during the 16-5 win over the Washington Nationals at PNC Park.
April 12: Philadelphia Phillies mascot, The Phanatic, entertains fans with local team mascots for a birthday celebration before the game against the Arizona Diamondbacks at Citizens Bank Park.
April 11: The Tampa Bay Rays' Jonathan Aranda (left) celebrates with Ryan Vilade after hitting a walk-off single against the New York Yankees in the 10th inning of a 5-4 win at Tropicana Field.
The Cleveland Guardians' Jose Ramirez acknowledges the fans after becoming the team's all-time leader in games played against the Kansas City Royals at Progressive Field on April 6, 2026.
A rainbow appears during the fourth inning during the game between the San Diego Padres and Pittsburgh Pirates at PNC Park on April 6, 2026.
A fan dresses as the Pope claps during the first inning of the game between the Chicago White Sox and Toronto Blue Jays at Rate Field on April 5, 2026. The White Sox won the game, 3-0, to complete a three-game sweep of the Blue Jays.
The Pittsburgh Pirates' Konnor Griffin celebrates with a traffic cone after making his major-league debut in a 5-4 defeat of the Baltimore Orioles at PNC Park on April 3, 2026.
A young Red Sox fan meets Tessie the Boston Red Sox mascot before the Red Sox's home opener against the San Diego Padres at Fenway Park on April 3, 2026.
Cleveland Guardians players warm up as the launch of NASA's Artemis II is shown on the center-field video board at Dodger Stadium on April 1, 2026.
Miami Marlins shortstop Otto Lopez (6) and center fielder Jakob Marsee celebrate a victory against the Chicago White Sox at loanDepot Park on April 1, 2026.
Fans try to catch a solo home run hit by the San Francisco Giants' Matt Chapman as San Diego Padres left fielder Nick Castellanos looks on during the third inning at Petco Park on March 31, 2026.
Philadelphia Phillies mascot The Phillie Phanatic entertains fans during the game against the Washington Nationals at Citizens Bank Park on March 31, 2026.
The Toronto Blue Jays' Kazuma Okamoto gets doused with ice water by teammates after a win over the Athletics at Rogers Centre on March 29, 2026.
The Cincinnati Reds' Eugenio Suárez blows a bubble as he waits to bat against the Boston Red Sox at Great American Ball Park on March 28, 2026.
The St. Louis Cardinals' JJ Wetherholt is doused with water by teammates after hitting a walk-off two-run single against the Tampa Bay Rays during the 10th inning at Busch Stadium on March 28, 2026.
Fans react as the Milwaukee Brewers' Jake Bauers homers against the Chicago White Sox at American Family Field on March 26, 2026.
Two F-35C planes from Air Test and Evaluation Squadron NINE Detachment Edwards Air Force Base perform a flyover before the Opening Day game between the Arizona Diamondbacks and Los Angeles Dodgers at Dodger Stadium on March 26, 2026.
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The Athletics Lawrence Butler is tagged out by Chicago White Sox third baseman Miguel Vargas as he tires to extend his double into a triple during the eighth inning at Sutter Health Park on April 18, 2026.
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The Athletics Lawrence Butler is tagged out by Chicago White Sox third baseman Miguel Vargas as he tires to extend his double into a triple during the eighth inning at Sutter Health Park on April 18, 2026.
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Cleveland Guardians mascot Slider interacts with fans during game against the Baltimore Orioles at Progressive Field on April 17, 2026.
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Washington Nationals right fielder Daylen Lile attempts to catch a ball hit for a single by the Pittsburgh Pirates' Jake Mangum during the first inning at PNC Park on April 16, 2026. The Nationals won the game, 8-7.
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Milwaukee Brewers catcher Gary Sanchez wears a special chest protector to commemorate Jackie Robinson Day during the game against the Toronto Blue Jays at American Family Field on April 15, 2026.
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April 13: The Pittsburgh Pirates' Spencer Horwitz celebrates a home run in the dugout while wearing a welder's hood during the 16-5 win over the Washington Nationals at PNC Park.
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April 12: Philadelphia Phillies mascot, The Phanatic, entertains fans with local team mascots for a birthday celebration before the game against the Arizona Diamondbacks at Citizens Bank Park.
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April 11: The Tampa Bay Rays' Jonathan Aranda (left) celebrates with Ryan Vilade after hitting a walk-off single against the New York Yankees in the 10th inning of a 5-4 win at Tropicana Field.
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The Cleveland Guardians' Jose Ramirez acknowledges the fans after becoming the team's all-time leader in games played against the Kansas City Royals at Progressive Field on April 6, 2026.
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A rainbow appears during the fourth inning during the game between the San Diego Padres and Pittsburgh Pirates at PNC Park on April 6, 2026.
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A fan dresses as the Pope claps during the first inning of the game between the Chicago White Sox and Toronto Blue Jays at Rate Field on April 5, 2026. The White Sox won the game, 3-0, to complete a three-game sweep of the Blue Jays.
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The Pittsburgh Pirates' Konnor Griffin celebrates with a traffic cone after making his major-league debut in a 5-4 defeat of the Baltimore Orioles at PNC Park on April 3, 2026.
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A young Red Sox fan meets Tessie the Boston Red Sox mascot before the Red Sox's home opener against the San Diego Padres at Fenway Park on April 3, 2026.
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Cleveland Guardians players warm up as the launch of NASA's Artemis II is shown on the center-field video board at Dodger Stadium on April 1, 2026.
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Miami Marlins shortstop Otto Lopez (6) and center fielder Jakob Marsee celebrate a victory against the Chicago White Sox at loanDepot Park on April 1, 2026.
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Fans try to catch a solo home run hit by the San Francisco Giants' Matt Chapman as San Diego Padres left fielder Nick Castellanos looks on during the third inning at Petco Park on March 31, 2026.
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Philadelphia Phillies mascot The Phillie Phanatic entertains fans during the game against the Washington Nationals at Citizens Bank Park on March 31, 2026.
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The Toronto Blue Jays' Kazuma Okamoto gets doused with ice water by teammates after a win over the Athletics at Rogers Centre on March 29, 2026.
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The Cincinnati Reds' Eugenio Suárez blows a bubble as he waits to bat against the Boston Red Sox at Great American Ball Park on March 28, 2026.
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The St. Louis Cardinals' JJ Wetherholt is doused with water by teammates after hitting a walk-off two-run single against the Tampa Bay Rays during the 10th inning at Busch Stadium on March 28, 2026.
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Fans react as the Milwaukee Brewers' Jake Bauers homers against the Chicago White Sox at American Family Field on March 26, 2026.
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Two F-35C planes from Air Test and Evaluation Squadron NINE Detachment Edwards Air Force Base perform a flyover before the Opening Day game between the Arizona Diamondbacks and Los Angeles Dodgers at Dodger Stadium on March 26, 2026.
Weathers was working on eight days of rest, because he fell ill the day of his most recent start on May 2. He spent the next couple of days with his insides turned out, leading to the nine-pound weight loss.
A further indignity: Weathers and his wife Thayer welcomed their first child, Paul David Weathers, on April 22. Weathers’ virus meant he had to sleep on a different floor at home than wife and newborn.
“It’s definitely been a couple weeks, for sure,” says Weathers. “But that doesn’t stop me from doing my job.
“My job is to go out and compete and throw up as many zeroes and get as many outs as I can get.”
Adding to the drama: His time in the Yankees rotation was ticking down as he recovered. Left-hander Carlos Rodón returned from off-season elbow surgery on May 10; Rodón’s procedure largely spurred the Yankees to acquire Weathers from Miami in the off-season.
And ace Gerrit Cole has now made five rehab starts and should line up to rejoin the rotation by month’s end.
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With his future in flux, Weathers went out and pitched the game of his life – even as he was unaware he was tossing a no-hitter.
He’d never thrown a complete game in 62 career starts and hadn’t thrown more than 101 pitches in a start this season. So at 85 pitches through six no-hit innings, it figured he wouldn’t finish a solo no-hitter.
Yet Weathers bedeviled the Orioles, striking out nine and using an almost equal four-pitch mix of changeup, his sinking and four-seam fastballs and sweeper. The no-hitter was intact until Adley Rutschman – the only Oriole who hit the ball hard off Weathers this night – poked a single to the right of second base.
When Weathers issued just his second walk of the game to Tyler O’Neill, manager Aaron Boone went and got him. With the Yankees suffering three narrow losses at Milwaukee before arriving here, relievers Tim Hill and Fernando Cruz were down.
Headrick was summoned to face the righty-swinging, but .158-hitting Mayo. Boone liked Headrick’s slider against Mayo. Mayo liked the slider Headrick threw him, clubbing it 389 feet out to left field.
A 2-0 lead became a 3-2 deficit. And with the Yankees struggling offensively, that was that.
And Weathers, through little fault of his own, was the losing pitcher.
New York Yankees pitcher Ryan Weathers delivers during the second inning against the Baltimore Orioles at Oriole Park at Camden Yards on May 11, 2026.
“We’ve scored zero, three, three, two,” says Boone of the skid that started in Milwaukee. “Pitching’s been there. Continues to be there.
“We gotta get some guys unlocked. We got a handful of guys scuffling.”
None more than Jazz Chisholm, who went 0-for-4 with three strikeouts and is in an 8-for-48 slide, with one extra-base hit in that span. He refused comment after the game.
Despite the skid, the Yankees are still 26-16, though they now trail Tampa Bay by two games.
Weathers, too, has a deficit to make up: He has not gained back all of his nine pounds, noting he needed to re-hydrate initially and then coax some food down after a couple days.
“I’m sneaking,” he said of gaining back all the weight he lost off his 6-foot-1, 230-pound frame. “I’m sneaking.”
Just not quite enough to add a historic night to his career.
This article originally appeared on USA TODAY: Ryan Weathers carries no-hitter into seventh, only for Yankees to lose